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A 2026 paper in Gut genetically mapped stool frequency across more than 268,000 people, using it as a proxy for gut motility.

Using a large multi-ancestry GWAS and Mendelian randomization, the authors showed that gut transit has a measurable genetic
Cluster headache (CH) is often called “the worst pain a human can experience.” Not migraine. Not kidney stones. Not childbirth. People pace, cry, hit walls, and some describe it as impossible to think through.

CH is not “a bad head
You snap out of a post-concussion fog to find your hands trembling, only to realize you haven’t eaten all day. If a brain injury has left you missing your hunger cues until you’re shaky with low blood sugar symptoms, you’re not lazy
Sex hurts AND you keep getting “UTls after sex” (or burning and urgency with negative cultures)? The missing link is often pelvic floor + bladder emptying + hormones + nerves + microbiome.

The loop we see constantly: pain, dryness, infla

 

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A 2026 paper in Gut genetically mapped stool frequency across more than 268,000 people, using it as a proxy for gut motility.

Using a large multi-ancestry GWAS and Mendelian randomization, the authors showed that gut transit has a measurable genetic
Cluster headache (CH) is often called “the worst pain a human can experience.” Not migraine. Not kidney stones. Not childbirth. People pace, cry, hit walls, and some describe it as impossible to think through.

CH is not “a bad head

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